The only versions of the OS X client that Apple supports in virtualization are those that do not include the Rosetta translator (OS X 10.7 and higher) which is required for running older PowerPC code on an Intel-based Mac. Unfortunately for Mac users, CS2 is a PowerPC application, so it will require the use of either an Intel Mac running OS X 10.4 through 10.6 with the Rosetta translator installed, or the use of an older PowerPC Mac. Nevertheless, if you have an older computer or have virtual-machine software configured with an older operating system compatible with CS2, then you should be able to get CS2 running.
Apple M1 Macs get a fast, new version of Adobe Lightroom Classic.